When I'm debugging my Asp.net applications, I find myself just wanting a quick and easy way of starting the asp.net web server. You can do this from the command line like this:
"C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\WebDev.WebServer.exe" /path:[PATH OF YOUR WEB APP] /port:[WEB PORT] /vpath:[/mywebapp]
You can also use the funky explorer plug-in designed by Robert McClaws here. This lets you run the webserver just by right clicking on a folder path.